Safe TNF-based antitumor therapy following p55TNFR reduction in intestinal epithelium

TNF has remarkable antitumor activities; however, therapeutic applications have not been possible because of the systemic and lethal proinflammatory effects induced by TNF. Both the antitumor and inflammatory effects of TNF are mediated by the TNF receptor p55 (p55TNFR) (encoded by the Tnfrsf1a gene...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Van Hauwermeiren, Filip, Armaka, Marietta, Karagianni, Niki, Kranidioti, Ksanthi, Vandenbroucke, Roosmarijn E., Loges, Sonja, Van Roy, Maarten, Staelens, Jan, Puimège, Leen, Palagani, Ajay, Berghe, Wim Vanden, Victoratos, Panayiotis, Carmeliet, Peter, Libert, Claude, Kollias, George
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668821/
https://ncbi.nlm.nih.gov/pubmed/23676465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65624
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker