Glucocorticoid-induced microRNA-511 protects against TNF by down-regulating TNFR1

TNF is a central actor during inflammation and a well-recognized drug target for inflammatory diseases. We found that the mouse strain SPRET/Ei, known for extreme and dominant resistance against TNF-induced shock, displays weak expression of TNF receptor 1 protein (TNFR1) but normal mRNA expression,...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:EMBO Mol Med
Hlavní autoři: Puimège, Leen, Van Hauwermeiren, Filip, Steeland, Sophie, Van Ryckeghem, Sara, Vandewalle, Jolien, Lodens, Sofie, Dejager, Lien, Vandevyver, Sofie, Staelens, Jan, Timmermans, Steven, Vandenbroucke, Roosmarijn E, Libert, Claude
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons, Ltd 2015
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4551340/
https://ncbi.nlm.nih.gov/pubmed/25995337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201405010
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky