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Crystal structure of human angiogenin with an engineered loop exhibits conformational flexibility at the functional regions of the molecule()

Human angiogenin (ANG) is an angiogenic molecule and a ribonucleolytic enzyme with significant amino acid sequence identity to pancreatic RNase A, plays a critical role in the establishment and growth of tumours. An association between ANG and cancer has been observed in more than 25 clinical studie...

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Bibliografski detalji
Glavni autori: Thiyagarajan, Nethaji, Acharya, K. Ravi
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668512/
https://ncbi.nlm.nih.gov/pubmed/23772376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2012.12.003
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