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Crystal structure of human angiogenin with an engineered loop exhibits conformational flexibility at the functional regions of the molecule()
Human angiogenin (ANG) is an angiogenic molecule and a ribonucleolytic enzyme with significant amino acid sequence identity to pancreatic RNase A, plays a critical role in the establishment and growth of tumours. An association between ANG and cancer has been observed in more than 25 clinical studie...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Elsevier
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3668512/ https://ncbi.nlm.nih.gov/pubmed/23772376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2012.12.003 |
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