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Structural and molecular insights into the mechanism of action of human angiogenin-ALS variants in neurons
Mutations in angiogenin (ANG), a member of the ribonuclease A superfamily, are associated with amyotrophic lateral sclerosis (ALS; sporadic and familial) and Parkinson's disease. We have previously shown that ANG is expressed in neurons during neuro-ectodermal differentiation, and that it has b...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Pub. Group
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3493651/ https://ncbi.nlm.nih.gov/pubmed/23047679 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2126 |
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