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The catalytic activity and secretion of zebrafish RNases are essential for their in vivo function in motor neurons and vasculature
Angiogenin (hANG), a member of the Ribonuclease A superfamily has angiogenic, neurotrophic and neuroprotective activities. Mutations in hANG have been found in patients with Amyotrophic lateral sclerosis (ALS). The zebrafish (Danio rerio) rnasel-1, 2 and 3 are orthologues of hANG and of these only R...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6358602/ https://ncbi.nlm.nih.gov/pubmed/30710110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37140-2 |
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