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Structure of murine angiogenin: Features of the substrate- and cell-binding regions and prospects for inhibitor-binding studies

Angiogenin is an unusual member of the pancreatic ribonuclease superfamily that induces blood vessel formation and is a promising anticancer target. The three-dimensional structure of murine angiogenin (mAng) has been determined by X-ray crystallography. Two structures are presented, one a complex w...

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Autors principals: Holloway, Daniel E., Chavali, Gayatri B., Hares, Michelle C., Subramanian, Vasanta, Ravi Acharya, K.
Format: Artigo
Idioma:Inglês
Publicat: 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1780170/
https://ncbi.nlm.nih.gov/pubmed/16301790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444905029616
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