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Crystal structures of murine angiogenin-2 and -3 – probing ‘structure – function’ relationships amongst angiogenin homologues

Angiogenin (Ang) is a potent inducer of neovascularization. Point mutations in human Ang have been linked to cancer progression and two neurodegenerative diseases: amyotrophic lateral sclerosis and Parkinson's disease. Intensive structural and functional analyses of Ang have been paramount in a...

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Detalhes bibliográficos
Main Authors: Iyer, Shalini, Holloway, Daniel E, Acharya, K Ravi
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Inc 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3572582/
https://ncbi.nlm.nih.gov/pubmed/23170778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.12071
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