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Structural insights into human angiogenin variants implicated in Parkinson’s disease and Amyotrophic Lateral Sclerosis

Mutations in Angiogenin (ANG), a member of the Ribonuclease A superfamily (also known as RNase 5) are known to be associated with Amyotrophic Lateral Sclerosis (ALS, motor neurone disease) (sporadic and familial) and Parkinson’s Disease (PD). In our previous studies we have shown that ANG is express...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Bradshaw, William J., Rehman, Saima, Pham, Tram T. K., Thiyagarajan, Nethaji, Lee, Rebecca L., Subramanian, Vasanta, Acharya, K. Ravi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5296752/
https://ncbi.nlm.nih.gov/pubmed/28176817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41996
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