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Structural insights into human angiogenin variants implicated in Parkinson’s disease and Amyotrophic Lateral Sclerosis

Mutations in Angiogenin (ANG), a member of the Ribonuclease A superfamily (also known as RNase 5) are known to be associated with Amyotrophic Lateral Sclerosis (ALS, motor neurone disease) (sporadic and familial) and Parkinson’s Disease (PD). In our previous studies we have shown that ANG is express...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Bradshaw, William J., Rehman, Saima, Pham, Tram T. K., Thiyagarajan, Nethaji, Lee, Rebecca L., Subramanian, Vasanta, Acharya, K. Ravi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5296752/
https://ncbi.nlm.nih.gov/pubmed/28176817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41996
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