Langerhans Cells Are Not Required for Efficient Skin Graft Rejection

The mechanism of skin allograft rejection has been thought to require presentation of graft antigen by resident epidermal Langerhans cells (LCs). We have previously engineered mice that have a selective and constitutive absence of epidermal LCs. By using donor skin from these LC-deficient mice, we s...

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Autori principali: Obhrai, Jagdeep S., Oberbarnscheidt, Martin, Zhang, Na, Mueller, Daniel L., Shlomchik, Warren D., Lakkis, Fadi G., Shlomchik, Mark J., Kaplan, Daniel H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668350/
https://ncbi.nlm.nih.gov/pubmed/18337832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2008.52
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