Langerhans Cells Are Not Required for Efficient Skin Graft Rejection

The mechanism of skin allograft rejection has been thought to require presentation of graft antigen by resident epidermal Langerhans cells (LCs). We have previously engineered mice that have a selective and constitutive absence of epidermal LCs. By using donor skin from these LC-deficient mice, we s...

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Hauptverfasser: Obhrai, Jagdeep S., Oberbarnscheidt, Martin, Zhang, Na, Mueller, Daniel L., Shlomchik, Warren D., Lakkis, Fadi G., Shlomchik, Mark J., Kaplan, Daniel H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668350/
https://ncbi.nlm.nih.gov/pubmed/18337832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2008.52
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