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Type I interferons are not critical for skin allograft rejection or the generation of donor-specific CD8(+) memory T cells

Type I interferons (IFN-I) link innate to adaptive immunity in microbial infection, autoimmune disease, and tumor immunity. It is not known whether IFN-I have an equally central role in alloimmunity. Here we tested this possibility by studying skin allograft survival and donor-specific CD8(+) T cell...

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Detalhes bibliográficos
Main Authors: Oberbarnscheidt, Martin H., Obhrai, Jagdeep S., Williams, Amanda L., Rothstein, David M., Shlomchik, Warren D., Chalasani, Geetha, Lakkis, Fadi G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806930/
https://ncbi.nlm.nih.gov/pubmed/19951284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2009.02871.x
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