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Innate immunity alone is not sufficient for chronic rejection but predisposes healed allografts to T cell-mediated pathology()

BACKGROUND: Acute allograft rejection is dependent on adaptive immunity, but it is unclear whether the same is true for chronic rejection. Here we asked whether innate immunity alone is sufficient for causing chronic rejection of mouse cardiac allografts. METHODS: We transplanted primarily vasculari...

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Hlavní autoři: Zecher, Daniel, Li, Qi, Williams, Amanda L., Walters, John T., Baddoura, Fady K., Chalasani, Geetha, Rothstein, David M., Shlomchik, Warren D., Demetris, Anthony J., Lakkis, Fadi G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277291/
https://ncbi.nlm.nih.gov/pubmed/22226941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trim.2011.12.006
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