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Non-self recognition by monocytes initiates allograft rejection
Maturation of T cell–activating APCs directly links innate and adaptive immunity and is typically triggered by microbial infection. Transplantation of allografts, which are sterile, generates strong T cell responses; however, it is unclear how grafts induce APC maturation in the absence of microbial...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4109551/ https://ncbi.nlm.nih.gov/pubmed/24983319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI74370 |
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