Autocrine/paracrine TGFβ1 is required for the development of epidermal Langerhans cells

Langerhans cells (LCs) are bone marrow (BM)–derived epidermal dendritic cells (DCs) that develop from precursors found in the dermis. Epidermal LCs are absent in transforming growth factor (TGF) β1-deficient mice. It is not clear whether TGFβ1 acts directly on LC precursors to promote maturation or...

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Dades bibliogràfiques
Autors principals: Kaplan, Daniel H., Li, Ming O., Jenison, Matthew C., Shlomchik, Warren D., Flavell, Richard A., Shlomchik, Mark J.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2007
Matèries:
Brief Definitive Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118472/
https://ncbi.nlm.nih.gov/pubmed/17938236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20071401
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