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XIAP gene expression and function is regulated by autocrine and paracrine TGF-β signaling

<p>Abstract</p> <p>Background</p> <p>X-linked inhibitor of apoptosis protein (XIAP) is often overexpressed in cancer cells, where it plays a key role in survival and also promotes invasiveness. To date however, the extracellular signals and intracellular pathways regula...

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Detalhes bibliográficos
Main Authors: Van Themsche Céline, Chaudhry Parvesh, Leblanc Valérie, Parent Sophie, Asselin Eric
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2010-08-01
Colecção:Molecular Cancer
Acesso em linha:http://www.molecular-cancer.com/content/9/1/216
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