XIAP gene expression and function is regulated by autocrine and paracrine TGF-β signaling

BACKGROUND: X-linked inhibitor of apoptosis protein (XIAP) is often overexpressed in cancer cells, where it plays a key role in survival and also promotes invasiveness. To date however, the extracellular signals and intracellular pathways regulating its expression and activity remain incompletely un...

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Bibliographic Details
Main Authors: Van Themsche, Céline, Chaudhry, Parvesh, Leblanc, Valérie, Parent, Sophie, Asselin, Eric
Format: Artigo
Language:Inglês
Published: BioMed Central 2010
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933620/
https://ncbi.nlm.nih.gov/pubmed/20712893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-216
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