Autocrine/paracrine TGFβ1 is required for the development of epidermal Langerhans cells

Langerhans cells (LCs) are bone marrow (BM)–derived epidermal dendritic cells (DCs) that develop from precursors found in the dermis. Epidermal LCs are absent in transforming growth factor (TGF) β1-deficient mice. It is not clear whether TGFβ1 acts directly on LC precursors to promote maturation or...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Kaplan, Daniel H., Li, Ming O., Jenison, Matthew C., Shlomchik, Warren D., Flavell, Richard A., Shlomchik, Mark J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Rockefeller University Press 2007
Aiheet:
Brief Definitive Reports
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118472/
https://ncbi.nlm.nih.gov/pubmed/17938236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20071401
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