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Neurotoxic amyloid beta oligomeric assemblies recreated in microfluidic platform with interstitial level of slow flow

Alzheimer's disease is accompanied by progressive, time-dependent changes of three moieties of amyloid beta. In vitro models therefore should provide same conditions for more physiologic studies. Here we observed changes in the number of fibrils over time and studied the correlation between amy...

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Autori principali: Choi, Yoon Jung, Chae, Sukyung, Kim, Jeong Hun, Barald, Kate F., Park, Joong Yull, Lee, Sang-Hoon
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667571/
https://ncbi.nlm.nih.gov/pubmed/23719665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01921
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