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Automated Ex Situ Assays of Amyloid Formation on a Microfluidic Platform

Increasingly prevalent neurodegenerative diseases are associated with the formation of nanoscale amyloid aggregates from normally soluble peptides and proteins. A widely used strategy for following the aggregation process and defining its kinetics involves the use of extrinsic dyes that undergo a sp...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Saar, Kadi-Liis, Yates, Emma V., Müller, Thomas, Saunier, Séverine, Dobson, Christopher M., Knowles, Tuomas P.J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4744157/
https://ncbi.nlm.nih.gov/pubmed/26840721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.11.3523
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