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Automated Ex Situ Assays of Amyloid Formation on a Microfluidic Platform

Increasingly prevalent neurodegenerative diseases are associated with the formation of nanoscale amyloid aggregates from normally soluble peptides and proteins. A widely used strategy for following the aggregation process and defining its kinetics involves the use of extrinsic dyes that undergo a sp...

詳細記述

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書誌詳細
出版年:Biophys J
主要な著者: Saar, Kadi-Liis, Yates, Emma V., Müller, Thomas, Saunier, Séverine, Dobson, Christopher M., Knowles, Tuomas P.J.
フォーマット: Artigo
言語:Inglês
出版事項: The Biophysical Society 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4744157/
https://ncbi.nlm.nih.gov/pubmed/26840721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.11.3523
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