Neurotoxic amyloid beta oligomeric assemblies recreated in microfluidic platform with interstitial level of slow flow

Alzheimer's disease is accompanied by progressive, time-dependent changes of three moieties of amyloid beta. In vitro models therefore should provide same conditions for more physiologic studies. Here we observed changes in the number of fibrils over time and studied the correlation between amy...

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Hauptverfasser: Choi, Yoon Jung, Chae, Sukyung, Kim, Jeong Hun, Barald, Kate F., Park, Joong Yull, Lee, Sang-Hoon
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667571/
https://ncbi.nlm.nih.gov/pubmed/23719665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01921
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