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Hierarchical Organization of Multi-Site Phosphorylation at the CXCR4 C Terminus

The chemokine receptor CXCR4 regulates cell migration during ontogenesis and disease states including cancer and inflammation. Upon stimulation by the endogenous ligand CXCL12, CXCR4 becomes phosphorylated at multiple sites in its C-terminal domain. Mutations in the CXCR4 gene affecting C-terminal p...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mueller, Wiebke, Schütz, Dagmar, Nagel, Falko, Schulz, Stefan, Stumm, Ralf
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666969/
https://ncbi.nlm.nih.gov/pubmed/23734232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064975
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