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Hierarchical Organization of Multi-Site Phosphorylation at the CXCR4 C Terminus

The chemokine receptor CXCR4 regulates cell migration during ontogenesis and disease states including cancer and inflammation. Upon stimulation by the endogenous ligand CXCL12, CXCR4 becomes phosphorylated at multiple sites in its C-terminal domain. Mutations in the CXCR4 gene affecting C-terminal p...

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Bibliografski detalji
Glavni autori: Mueller, Wiebke, Schütz, Dagmar, Nagel, Falko, Schulz, Stefan, Stumm, Ralf
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666969/
https://ncbi.nlm.nih.gov/pubmed/23734232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064975
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