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Replication-Independent Repair of DNA Interstrand Crosslinks
DNA interstrand crosslinks (ICLs) are cytotoxic lesions that covalently link opposite strands of the DNA helix and block DNA unwinding. ICLs are repaired during and outside S phase, and replication-independent ICL repair (RIR) is critical to maintain genomic integrity and to allow transcription in n...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3666337/ https://ncbi.nlm.nih.gov/pubmed/22658724 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.05.001 |
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