Wordt geladen...

Checkpoint signaling from a single DNA interstrand crosslink

DNA interstrand crosslinks (ICLs) are the most toxic lesions induced by chemotherapeutic agents such as Mitomycin C and Cisplatin. By covalently linking both DNA strands, ICLs prevent DNA melting, transcription, and replication. Studies on ICL signaling and repair have been limited because these dru...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Ben-Yehoyada, Merav, Wang, Lily C., Kozekov, Ivan D., Rizzo, Carmelo J., Gottesman, Max E., Gautier, Jean
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756577/
https://ncbi.nlm.nih.gov/pubmed/19748363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.08.014
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!