Yes-Associated Protein Upregulates Jagged-1 and Activates the NOTCH Pathway in Human Hepatocellular Carcinoma

BACKGROUND & AIMS: Cancer cells often lose contact inhibition to undergo anchorage-independent proliferation and become resistant to apoptosis by inactivating the Hippo signaling pathway, resulting in activation of the transcriptional co-activator yes-associated protein (YAP). However, the oncog...

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Détails bibliographiques
Auteurs principaux: Tschaharganeh, Darjus Felix, Chen, Xin, Latzko, Philipp, Malz, Mona, Gaida, Matthias Martin, Felix, Klaus, Ladu, Sara, Singer, Stephan, Pinna, Federico, Gretz, Norbert, Sticht, Carsten, Tomasi, Maria Lauda, Delogu, Salvatore, Evert, Matthias, Fan, Biao, Ribback, Silvia, Jiang, Lijie, Brozzetti, Stefania, Bergmann, Frank, Dombrowski, Frank, Schirmacher, Peter, Calvisi, Diego Francesco, Breuhahn, Kai
Format: Artigo
Langue:Inglês
Publié: 2013
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665638/
https://ncbi.nlm.nih.gov/pubmed/23419361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2013.02.009
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