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Contribution of Factor VIII Light Chain Residues 2007–2016 to an Activated Protein C-Interactive Site

Although factor (F) VIIIa is inactivated by activated protein C (APC) through cleavages in the FVIII heavy chain-derived A1 (Arg(336)) and A2 subunits (Arg(562)), the FVIII light chain (LC) contributes to catalysis by binding the enzyme. ELISA-based binding assays showed that FVIII and FVIII LC boun...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Takeyama, Masahiro, Wakabayashi, Hironao, Fay, Philip J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665284/
https://ncbi.nlm.nih.gov/pubmed/23224054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH12-08-0561
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