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Ozone-Induced Injury and Oxidative Stress in Bronchiolar Epithelium Are Associated with Altered Pulmonary Mechanics

In these studies, we analyzed the effects of ozone on bronchiolar epithelium. Exposure of rats to ozone (2 ppm, 3h) resulted in rapid (within 3h) and persistent (up to 72h) histological changes in the bronchiolar epithelium, including hypercellularity, loss of cilia, and necrotizing bronchiolitis. P...

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書誌詳細
主要な著者: Sunil, Vasanthi R., Vayas, Kinal N., Massa, Christopher B., Gow, Andrew J., Laskin, Jeffrey D., Laskin, Debra L.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663562/
https://ncbi.nlm.nih.gov/pubmed/23492811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kft071
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