Ozone-Induced Injury and Oxidative Stress in Bronchiolar Epithelium Are Associated with Altered Pulmonary Mechanics

In these studies, we analyzed the effects of ozone on bronchiolar epithelium. Exposure of rats to ozone (2 ppm, 3h) resulted in rapid (within 3h) and persistent (up to 72h) histological changes in the bronchiolar epithelium, including hypercellularity, loss of cilia, and necrotizing bronchiolitis. P...

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Hauptverfasser: Sunil, Vasanthi R., Vayas, Kinal N., Massa, Christopher B., Gow, Andrew J., Laskin, Jeffrey D., Laskin, Debra L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663562/
https://ncbi.nlm.nih.gov/pubmed/23492811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kft071
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