Ozone-Induced Injury and Oxidative Stress in Bronchiolar Epithelium Are Associated with Altered Pulmonary Mechanics

In these studies, we analyzed the effects of ozone on bronchiolar epithelium. Exposure of rats to ozone (2 ppm, 3h) resulted in rapid (within 3h) and persistent (up to 72h) histological changes in the bronchiolar epithelium, including hypercellularity, loss of cilia, and necrotizing bronchiolitis. P...

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Hlavní autoři: Sunil, Vasanthi R., Vayas, Kinal N., Massa, Christopher B., Gow, Andrew J., Laskin, Jeffrey D., Laskin, Debra L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663562/
https://ncbi.nlm.nih.gov/pubmed/23492811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kft071
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