Ozone-Induced Injury and Oxidative Stress in Bronchiolar Epithelium Are Associated with Altered Pulmonary Mechanics

In these studies, we analyzed the effects of ozone on bronchiolar epithelium. Exposure of rats to ozone (2 ppm, 3h) resulted in rapid (within 3h) and persistent (up to 72h) histological changes in the bronchiolar epithelium, including hypercellularity, loss of cilia, and necrotizing bronchiolitis. P...

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Main Authors: Sunil, Vasanthi R., Vayas, Kinal N., Massa, Christopher B., Gow, Andrew J., Laskin, Jeffrey D., Laskin, Debra L.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663562/
https://ncbi.nlm.nih.gov/pubmed/23492811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kft071
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