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The Kindlin 3 Pleckstrin Homology Domain Has an Essential Role in Lymphocyte Function-associated Antigen 1 (LFA-1) Integrin-mediated B Cell Adhesion and Migration

The protein kindlin 3 is mutated in the leukocyte adhesion deficiency III (LAD-III) disorder, leading to widespread infection due to the failure of leukocytes to migrate into infected tissue sites. To gain understanding of how kindlin 3 controls leukocyte function, we have focused on its pleckstrin...

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Detalhes bibliográficos
Main Authors: Hart, Rosie, Stanley, Paula, Chakravarty, Probir, Hogg, Nancy
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663508/
https://ncbi.nlm.nih.gov/pubmed/23595985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.434621
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