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Mitonuclear protein imbalance as a conserved longevity mechanism
Longevity is regulated by a network of intimately linked metabolic systems. We used a combination of mouse population genetics and RNAi in C. elegans to identify mitochondrial ribosomal protein S5 (Mrps5) and other mitochondrial ribosomal proteins (MRPs) as metabolic and longevity regulators. MRP kn...
Tallennettuna:
| Päätekijät: | , , , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2013
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3663447/ https://ncbi.nlm.nih.gov/pubmed/23698443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12188 |
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