PARP1 is required for chromosomal translocations

Chromosomal translocations are common contributors to malignancy, yet little is known about the precise molecular mechanisms by which they are generated. Sequencing translocation junctions in acute leukemias revealed that the translocations were likely mediated by a DNA double-strand break repair pa...

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Bibliografske podrobnosti
Main Authors: Wray, Justin, Williamson, Elizabeth A., Singh, Sudha B., Wu, Yuehan, Cogle, Christopher R., Weinstock, David M., Zhang, Yu, Lee, Suk-Hee, Zhou, Daohong, Shao, Lijian, Hauer-Jensen, Martin, Pathak, Rupak, Klimek, Virginia, Nickoloff, Jac A., Hromas, Robert
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2013
Teme:
Myeloid Neoplasia
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663429/
https://ncbi.nlm.nih.gov/pubmed/23568489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-10-460527
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