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The Transposase Domain Protein Metnase/SETMAR Suppresses Chromosomal Translocations
Chromosomal translocations are common in leukemia, but little is known about their mechanism. Metnase (also termed SETMAR) is a fusion of a histone methylase and transposase protein that arose specifically in primates. Transposases were thought to be extinct in primates because they would mediate de...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2904321/ https://ncbi.nlm.nih.gov/pubmed/20620605 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cancergencyto.2010.04.011 |
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