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THE HUMAN SET AND TRANSPOSASE DOMAIN PROTEIN METNASE INTERACTS WITH DNA LIGASE IV AND ENHANCES THE EFFICIENCY AND ACCURACY OF NON-HOMOLOGOUS END JOINING

Transposase domain proteins mediate DNA movement from one location in the genome to another in lower organisms. However, in human cells such DNA mobility would be deleterious, and therefore the vast majority of transposase-related sequences in humans are pseudogenes. We recently isolated and charact...

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Bibliographic Details
Main Authors: Hromas, Robert, Wray, Justin, Lee, Suk-Hee, Martinez, Leah, Farrington, Jacqueline, Corwin, Lori Kwan, Ramsey, Heather, Nickoloff, Jac A., Williamson, Elizabeth A.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644637/
https://ncbi.nlm.nih.gov/pubmed/18773976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2008.08.002
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