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The SET domain protein Metnase mediates foreign DNA integration and links integration to nonhomologous end-joining repair
The molecular mechanism by which foreign DNA integrates into the human genome is poorly understood yet critical to many disease processes, including retroviral infection and carcinogenesis, and to gene therapy. We hypothesized that the mechanism of genomic integration may be similar to transposition...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1312370/ https://ncbi.nlm.nih.gov/pubmed/16332963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0503676102 |
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