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Methylation of histone H3 lysine 36 enhances DNA repair by nonhomologous end-joining

Given its significant role in the maintenance of genomic stability, histone methylation has been postulated to regulate DNA repair. Histone methylation mediates localization of 53BP1 to a DNA double-strand break (DSB) during homologous recombination repair, but a role in DSB repair by nonhomologous...

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Detalhes bibliográficos
Main Authors: Fnu, Sheema, Williamson, Elizabeth A., De Haro, Leyma P., Brenneman, Mark, Wray, Justin, Shaheen, Montaser, Radhakrishnan, Krishnan, Lee, Suk-Hee, Nickoloff, Jac A., Hromas, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021059/
https://ncbi.nlm.nih.gov/pubmed/21187428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1013571108
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