Keto-Mycolic Acid-Dependent Pellicle Formation Confers Tolerance to Drug-Sensitive Mycobacterium tuberculosis

The chronic nature of tuberculosis (TB), its requirement of long duration of treatment, its ability to evade immune intervention, and its propensity to relapse after drug treatment is discontinued are reminiscent of other chronic, biofilm-associated bacterial diseases. Historically, Mycobacterium tu...

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Detalhes bibliográficos
Main Authors: Sambandan, Dhinakaran, Dao, Dee N., Weinrick, Brian C., Vilchèze, Catherine, Gurcha, Sudagar S., Ojha, Anil, Kremer, Laurent, Besra, Gurdyal S., Hatfull, Graham F., Jacobs, William R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663190/
https://ncbi.nlm.nih.gov/pubmed/23653446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00222-13
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