Temperature-dependent Regulation of Mycolic Acid Cyclopropanation in Saprophytic Mycobacteria: ROLE OF THE MYCOBACTERIUM SMEGMATIS 1351 GENE (MSMEG_1351) IN CIS-CYCLOPROPANATION OF α-MYCOLATES

The cell envelope is a crucial determinant of virulence and drug resistance in Mycobacterium tuberculosis. Several features of pathogenesis and immunomodulation of host responses are attributable to the structural diversity in cell wall lipids, particularly in the mycolic acids. Structural modificat...

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Autori principali: Alibaud, Laeticia, Alahari, Anuradha, Trivelli, Xavier, Ojha, Anil K., Hatfull, Graham F., Guerardel, Yann, Kremer, Laurent
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2010
Soggetti:
Microbiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898377/
https://ncbi.nlm.nih.gov/pubmed/20457615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.125724
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