Growth of Mycobacterium tuberculosis biofilms containing free mycolic acids and harbouring drug-tolerant bacteria

Successful treatment of human tuberculosis requires 6–9 months' therapy with multiple antibiotics. Incomplete clearance of tubercle bacilli frequently results in disease relapse, presumably as a result of reactivation of persistent drug-tolerant Mycobacterium tuberculosis cells, although the na...

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Autors principals: Ojha, Anil K, Baughn, Anthony D, Sambandan, Dhinakaran, Hsu, Tsungda, Trivelli, Xavier, Guerardel, Yann, Alahari, Anuradha, Kremer, Laurent, Jacobs, William R, Hatfull, Graham F
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2008
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615189/
https://ncbi.nlm.nih.gov/pubmed/18466296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2008.06274.x
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