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Pathway to Synthesis and Processing of Mycolic Acids in Mycobacterium tuberculosis

Mycobacterium tuberculosis is known to synthesize α-, methoxy-, and keto-mycolic acids. We propose a detailed pathway to the biosynthesis of all mycolic acids in M. tuberculosis. Fatty acid synthetase I provides C(20)-S-coenzyme A to the fatty acid synthetase II system (FAS-IIA). Modules of FAS-IIA...

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Detalhes bibliográficos
Main Authors: Takayama, Kuni, Wang, Cindy, Besra, Gurdyal S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC544180/
https://ncbi.nlm.nih.gov/pubmed/15653820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CMR.18.1.81-101.2005
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