Pathway to Synthesis and Processing of Mycolic Acids in Mycobacterium tuberculosis

Mycobacterium tuberculosis is known to synthesize α-, methoxy-, and keto-mycolic acids. We propose a detailed pathway to the biosynthesis of all mycolic acids in M. tuberculosis. Fatty acid synthetase I provides C(20)-S-coenzyme A to the fatty acid synthetase II system (FAS-IIA). Modules of FAS-IIA...

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Pubblicato in:	Clin Microbiol Rev
Autori principali:	Takayama, Kuni, Wang, Cindy, Besra, Gurdyal S.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2005
Soggetti:	Reviews
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC544180/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15653820/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/CMR.18.1.81-101.2005
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