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Class A Scavenger Receptor 1 (MSR1) Restricts Hepatitis C Virus Replication by Mediating Toll-like Receptor 3 Recognition of Viral RNAs Produced in Neighboring Cells

Persistent infections with hepatitis C virus (HCV) may result in life-threatening liver disease, including cirrhosis and cancer, and impose an important burden on human health. Understanding how the virus is capable of achieving persistence in the majority of those infected is thus an important goal...

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Autors principals: Dansako, Hiromichi, Yamane, Daisuke, Welsch, Christoph, McGivern, David R., Hu, Fengyu, Kato, Nobuyuki, Lemon, Stanley M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3662657/
https://ncbi.nlm.nih.gov/pubmed/23717201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003345
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