Competing and noncompeting activities of miR-122 and the 5′ exonuclease Xrn1 in regulation of hepatitis C virus replication

Hepatitis C virus (HCV) replication is dependent on microRNA 122 (miR-122), a liver-specific microRNA that recruits Argonaute 2 to the 5′ end of the viral genome, stabilizing it and slowing its decay both in cell-free reactions and in infected cells. Here we describe the RNA degradation pathways aga...

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Detaylı Bibliyografya
Asıl Yazarlar: Li, You, Masaki, Takahiro, Yamane, Daisuke, McGivern, David R., Lemon, Stanley M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2013
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3562843/
https://ncbi.nlm.nih.gov/pubmed/23248316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1213515110
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