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miR-122 and the Hepatitis C RNA genome: More than just stability

MicroRNA-122 (miR-122) plays a key role in hepatitis C virus (HCV) replication, but understanding exactly how it functions in the viral lifecycle has been elusive. HCV is a positive-strand virus with a messenger-sense RNA genome, to which miR-122 binds in a non-canonical fashion at two sites near th...

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Detalhes bibliográficos
Main Authors: Li, You, Masaki, Takahiro, Lemon, Stanley M.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904590/
https://ncbi.nlm.nih.gov/pubmed/23770926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.25137
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