Genetic modulation of islet β-cell iPLA(2)β expression provides evidence for its impact on β-cell apoptosis and autophagy

β-cell apoptosis is a significant contributor to β-cell dysfunction in diabetes and ER stress is among the factors that contributes to β-cell death. We previously identified that the Ca(2+)-independent phospholipase A(2)β (iPLA(2)β), which in islets is localized in β-cells, participates in ER stress...

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Detalhes bibliográficos
Main Authors: Lei, Xiaoyong, Bone, Robert N., Ali, Tomader, Wohltmann, Mary, Gai, Ying, Goodwin, Karen J., Bohrer, Alan E., Turk, John, Ramanadham, Sasanka
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3662380/
https://ncbi.nlm.nih.gov/pubmed/23411472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/isl.23758
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