Apoptosis of Insulin-Secreting Cells Induced by Endoplasmic Reticulum Stress Is Amplified by Overexpression of Group VIA Calcium-Independent Phospholipase A(2) (iPLA(2)β) and Suppressed by Inhibition of iPLA(2)β

The death of insulin-secreting β-cells that causes type I diabetes mellitus (DM) occurs in part by apoptosis, and apoptosis also contributes to progressive β-cell dysfunction in type II DM. Recent reports indicate that ER stress-induced apoptosis contributes to β-cell loss in diabetes. Agents that d...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Ramanadham, Sasanka, Hsu, Fong-Fu, Zhang, Sheng, Jin, Chun, Bohrer, Alan, Song, Haowei, Bao, Shunzhong, Ma, Zhongmin, Turk, John
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3732319/
https://ncbi.nlm.nih.gov/pubmed/14744135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi035536m
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados