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Pancreatic Islets and Insulinoma Cells Express a Novel Isoform of Group VIA Phospholipase A(2) (iPLA(2)β) that Participates in Glucose-Stimulated Insulin Secretion and Is Not Produced by Alternate Splicing of the iPLA(2)β Transcript
Many cells express a group VIA 84 kDa phospholipase A(2) (iPLA(2)β) that is sensitive to inhibition by a bromoenol lactone (BEL) suicide substrate. Inhibition of iPLA(2)β in pancreatic islets and insulinoma cells suppresses, and overexpression of iPLA(2)β in INS-1 insulinoma cells amplifies, glucose...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2003
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3716001/ https://ncbi.nlm.nih.gov/pubmed/14636061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi034843p |
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