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Genetic modulation of islet β-cell iPLA(2)β expression provides evidence for its impact on β-cell apoptosis and autophagy
β-cell apoptosis is a significant contributor to β-cell dysfunction in diabetes and ER stress is among the factors that contributes to β-cell death. We previously identified that the Ca(2+)-independent phospholipase A(2)β (iPLA(2)β), which in islets is localized in β-cells, participates in ER stress...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Landes Bioscience
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3662380/ https://ncbi.nlm.nih.gov/pubmed/23411472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/isl.23758 |
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